|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.0 |
0.0 |
0.00079 |
0.0 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.0031 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
C
A
C
A
C
A
C
A
C
A
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.0 |
0.0 |
0.0 |
0.0017 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.087 |
0.57 |
0.73 |
0.58 |
0.46 |
|
A
C
A
C
G
C
A
C
G
C
A
C
A
C
A
C
A
C
A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.001 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.0 |
0.00086 |
0.0 |
0.0 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.074 |
0.014 |
0.0094 |
0.013 |
0.024 |
|
A
C
A
C
G
C
A
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.005 |
0.0 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.16 |
0.013 |
0.0 |
0.017 |
0.0033 |
|
A
C
A
C
G
C
A
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.0 |
0.00086 |
0.0 |
0.0 |
|
A
C
A
C
G
C
A
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.21 |
0.13 |
0.1 |
0.076 |
0.083 |
|
A
C
A
C
G
C
A
C
G
C
A
C
G
C
A
C
A
C
A
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A
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A
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A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.0 |
0.0 |
0.0 |
0.00083 |
|
A
C
A
C
G
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.086 |
0.0061 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.14 |
0.17 |
0.11 |
0.26 |
0.15 |
|
A
C
A
C
G
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0017 |
0.001 |
0.0017 |
0.0016 |
0.022 |
|
A
C
A
C
G
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.078 |
0.0061 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.0 |
0.0 |
0.0 |
0.00083 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.005 |
0.015 |
0.024 |
0.039 |
0.032 |
|
A
C
A
C
G
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.026 |
0.001 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.00056 |
0.0 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.001 |
0.0 |
0.0 |
0.0075 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.064 |
0.0072 |
0.00086 |
0.0071 |
0.00083 |
|
A
C
A
C
G
C
A
C
G
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.00056 |
0.0 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.001 |
0.014 |
0.0 |
0.18 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.066 |
0.0031 |
0.0 |
0.0047 |
0.0 |
|
A
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.046 |
0.0077 |
0.0 |
0.04 |
|
A
C
A
C
G
C
A
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0045 |
0.0 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.0051 |
0.0 |
0.0 |
0.0 |
|
A
C
A
C
G
C
G
C
A
C
A
C
A
C
A
C
A
C
A
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A
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A
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A
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A
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A
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A
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A
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A
C
A
C
A
C
A
C
A
C
T
C
T
C
A
C
A
C
A
C
A
|
0.0 |
0.002 |
0.0 |
0.0 |
0.0 |